Endometrial cancer

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I. The etiology and prevalence of

  • Incidence. Endometrial cancer - the most common malignant tumor of the female genital organs
  • Risk Factors

1. Estrogen. Estrogen without progestin increases the risk of endometrial cancer by 4-8 times.

2. Diseases accompanied by hyperestrogenism. These diseases also increase the risk of endometrial cancer.

  • Polycystic ovary syndrome (chronic anovulation in the background of hyperandrogenism after the exclusion of other causes of the latter).
  • Chronic anovulation.
  • Obesity.
  • folliculoma ovarian and other tumors estrogensekretiruyuschie.
  • Severe hepatic failure.

3. Other diseases and conditions that increase the risk of endometrial cancer

  • infertility, the absence of pregnancy, menstrual irregularities.
  • diabetes.
  • Hypertension.
  • Malignant tumors, the different localization in the family history.
  • breast cancer or colon in history.

II. Diagnosis

  • The clinical picture

Bloody discharge from the genitals - the most common complaint is that placing 97% of patients.

III. Treatment.

The early stages of

  • Surgical treatment of  
    • Abdominal hysterectomy with appendages - the operation of choice for cancer of the uterine body I and II (when there is no macroscopic lesions of the cervix), clinical stages in the absence of severe comorbidities.  
    • Stage II. In cancer, stage II endometrial spend a combined treatment (radiotherapy and surgery), or perform extended hysterectomy with appendages.
  • Radiation therapy  
    • Radiation therapy as an independent method of treatment is indicated for patients who because of severe comorbidities can not perform the operation.
    • Postoperative radiation therapy. To improve the accuracy of the morphological stages, many authors recommend that refuse to preoperative radiation therapy in the postoperative benefits.
  • Chemotherapy. This treatment is indicated for papillary serous and clear cell cancer of the uterus early stages
Cancer Treatments
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